Website Help: Create Quote: . Best service and qualified products will be offered. 156-54-7 Synonyms: Butyric Acid Molecular Formula: C4H7O2 Na Formula Weight: 110.1 Purity 98% Formulation: A crystalline solid Origin: Synthetic Storage: Room temperature . Document Type Product Name Catalog # Lot # Language Product Information Sheet 110.09. Molecular Weight: 110.09. View the Full Spectrum for FREE! Insoluble in ether. Sodium butyrate is a compound with formula Na. What are the molecular effects of . CAS Number: 156-54-7. 62601-04-1. 29156010. . Tel: 1-855-346 . Further, it is used in the determination of the role of histone acetylation in chromatin structure and function. It is the sodium salt of butyric acid. Antibodies used for western blotting purchased from Cell Signaling Technology or Abcam. Cambridge Isotope Laboratories offers SODIUM BUTYRATE (13C4, 99%) for all your research needs. Molecular Formula - C 4 H 7 NaO 2. Molecular Weight: 110.09 : Chemical structure: Molecular Formula: C 4 H 7 NaO 2: CAS Number: 156-54-7 : PubChem identifier: 5222465 : SMILES [Na+].CCCC([O-])=O : Packings. Sisco . Sodium butyrate 98+% . Sodium Butyrate contains not less than 98.0 percent and not more than 101.0 percent . Sodium butyrate induces the production of recombinant protein in Chinese hamster ovary (CHO) cells and other human cell lines. If it comes into contact with even a trace of moisture, it emits a faint odor of its foul-smelling conjugate acid. 156-54-7. Advanced Search. PubChem identifier. Chemical Purity. Reconstitution: For a 100 mM stock solution of Sodium Butyrate, add 9 mL of water to . Appearance is white or off-white powder, with a special odor like rancid cheese, and hygroscopic. Batch . Molecular Weight. The Properties, Specifications, Monograph and Uses of Sodium Butyrate & Encapsulated Sodium Butyrate: Sodium Butyrate CAS Number 156-54-7, EINECS EC Number 205-857-6, HS Code 29163990 or 29156000, Molecular Weight 110.09, Chemical Formula CH3CH2CH2COONa. Na Molecular Weight 110.1 g/mol Purity 95% Pathway Epigenetic Target HDAC View More Protocols and Documentation Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below. Further, it is used in the determination of the role of histone ac Specifications Certificates Certificate of Analysis (1) (All certificate documents open as a .pdf) Synonym(s): Butyric acid-13 C 4 sodium salt . Introduction: Sodium butyrate is a short chain fatty acid that has effects at the molecular, cellular, and tissue level. . . DOT Classification: Not a DOT controlled material (United States). Description: CAS Number: 156-54-7 MDL Number: MFCD00002816 Molecular Formula: C4H8O2 Molecular Weight: 110.09 Purity/Analysis Method: 98.0% (T) Form: Crys. Applications: Separation of Sodium butyrate on Newcrom R1 HPLC column Sodium butyrate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The butyrate ion, along with the analogous propionate ion, is purported to enhance gut health in humans and many other animal species. Specs. Name Sodium butyrate . C4H7NaO2. SODIUM BUTYRATE CAS No. 5222465. . 4.3. Show full entry for Butyric Acid. Sodium Succinate Specifications of Manufacturers. Sodium butyrate is a compound with formula Na (C3H7COO). Molecular Formula. SODIUM BUTYRATE (30-1946) View SDS. CAS No. Quality Level. . This study was designed to investigate the effects of supplementation with a combination of nicotinamide and butyrate . Sodium butyrate is a compound with formula Na (C 3 H 7 COO). View the Full . Catalog Number : 1565474 description Sodium Butyrate is the sodium salt of butyric acid that has the biological effect of inducing histone hyperacetylation and the inhibition of histone deacetylase (HDAC) activity. Molecular Weight: 110.08 g/mol Molecular Formula: C4H7NaO2 SMILES: CCCC(=O)O[Na] Canonical SMILES: CCCC(=O)O[Na] InChIKey Identifier: MFBOGIVSZKQAPD . Molecular Formula: C 4 H 7 O 2 Na. Butyric acid sodium salt. The following data is based on the product molecular weight 110.09. B. Inhibits histone deacetylase.Sodium butyrate is used in the treatment of human spinal muscular atrophy patients. Butyrate, a low-molecular weight four-carbon chain volatile fatty acid (VFA) has been previously shown to withdraw cells from cell cycle or to promote cell differentiation, and finally to induce . As such, it can be used in lab to bring about any of these effects. PMID 32555166; DOI 10.1038/s41419-020-2663-1; Cell death & disease 2020 06; 11 (6):469. Inquire with a Quick Quote Sodium Butyrate Quantity Unit CAS # 156-54-7 Get A Quick Quote Download product spec Download SDS Product Description PRODUCT Sodium Butyrate CAS # 156-54-7 SYNONYM Name: Sodium butyrate: Synonyms: . Molecular Weight* 114.06. Molecular weight. the natural function of butyrate in the colon is not fully understood, butyrate is a powerful antidote for ammonium and neurotoxin, which can promote the formation of fri. The sodium salt of 4-hydroxybutyric acid. Sodium Butyrate Granule 98% Minimum For Swine, Poultry And Aqua Active ingredient: Sodium butyrate Concentration: 98% Minimum Molecular Formula: C4H7O2Na Molecular weight: 110.09 Description: White to off White , ball shape granule, Particle Size is Similar to Feed, With light Rancid Odour, Stable to Light and Heat, Freely Soluble in Water.Main properties of sodium butyrate. Product Name & Other Names: Sodium Succinate CAS#: 150-90-3 EINECS EC Number: 205-778-7 Chemical Formula: NaOOCCH2CH2COONa Molecular Weight: 162.05 Chemsrc provides Sodium butyrate(CAS#:156-54-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. This review outlines the molecular events that accompany the antitumor action of sodium butyrate (NaBt). The density is 0.96 g/mL (25/4), the melting point is 250~253, and it is easily soluble in water and ethanol. (6-8 weeks old; weight 18-20 g) were purchased from the Jackson Laboratory and housed for one week prior to study (Bar Harbor, ME). One-way ANOVA analysis revealed a P -value of <0.0001. . Application: Sodium Butyrate is an HDAC inhibitor, apoptosis inducer and can induce differentiation and gene expression and also prevent cell proliferation. Sodium butyrate, a short-chain fatty acid, is the most common and physiologic member of HDAC inhibitors because it is formed in the colon by fermentation of dietary fibers. 100 gm | 500 gm. Ionic strength studies in the range of 0-5 mM NaH2PO4, 0.2 mM EDTA, pH 7.4, of high molecular weight chromatin exhibited a decrease in [theta]282.5 and a shifting of hyperchromicity from transition I to transition III with increasing ionic strength. We have investigated the neuroprotective effects of NaB in SH-SY5Y cells stimulated with TNF-. Evidence from. Sodium Butyrate MSDS (material safety data sheet) or SDS, COA and Specs . Molecular weight. It is readily available and inexpensive. Compare Product No. HSN Code - 2915.6010. As a component of intestinal microecological environment, its short-term effects on the human body are not obvious [ 8 ]. the natural function of butyrate in the colon is not fully understood, butyrate is a powerful antidote for ammonium and neurotoxin, which can promote the formation of fri. C 4 H 7 NaO 2. In recent years, increased attention has been focused on breast muscle yield and meat quality in poultry production. MDL number: MFCD00002816. Properties. Also improves cognitive function in Schizophrenia. Soluble in water, dimethyl sulfoxide and ethanol. Sodium butyrateProduct ingredient for Butyric Acid. 156-54-7 - MFBOGIVSZKQAPD-UHFFFAOYSA-M - Sodium butyrate [USP] - Similar structures search, synonyms, formulas, resource links, and other chemical information. : 156-54-7 Molecular Formula : C4H7O2Na SPECIFICATION : Appearance : White Free Flow Powder Assay : 98.4 % Min Loss on drying More A. Get contact details & address of companies engaged in wholesale trade, manufacturing and supplying Sodium Butyrate, Sodium Butanoate across India. Sodium Butyrate . n = 7. Another study investigated the impact of a feed additive containing exogenous enzymes, acidifiers, sodium butyrate, and nSiO 2 on the cellular immune indices and body weight gains of calves . ), and also reported no difference in weight gain in these fish fed with diets supplemented with sodium butyrate. Sodium butyrate (NaB) is a short-chain fatty acid produced by intestinal microflora during the anaerobic fermentation of dietary fiber [ 7 ]. Butyrate is the name of the conjugate base of butyric acid. Cambridge Isotope Laboratories offers SODIUM BUTYRATE (1-13C, 99%) for all your research needs. C4H7O2Na. Section 1: Chemical Product Identification. Chemical Structure - Sodium butyrate, Histone deacetylase inhibitor (ab120948) has been done on animals or isolated cells. The sodium atom has a radius of 185.8 pm and a Van der Waals radius of 227 pm. water, its solution is weakly alkaline Purity: 98%. Molecular Formula : C4H7O2Na Molecular Weight : 110.09 Part B Storage : Room Temperature Shelf Life : 60 Months . Sodium Butyrate is used in pharmaceutical drugs to improve passive absorption of water in the colon. Articles of Sodium butyrate are included as well. Sodium (atomic symbol: Na, atomic number: 11) is a Block D, Group 5, Period 4 element with an atomic weight of 22.989769. Effects of NaB on P-53 . Sodium butyrate is a short-chain fatty acid that inhibits histone deacetylase (HDAC) in the millimolar range. The invention provides a preparation method of sodium butyrate, and the method comprises the following steps: dropwisely adding butyric acid into an NaOH water solution to react; and after the. Target: Sodium b utyrate (0.25 - 5 mM) i nhibits histone deacetylase (HDAC) in cultured cells. Sodium butyrate is the sodium salt of the butyric acid, usually used in pharmacological studies. Solubility: This molecule is soluble in water at 900 mM. Sodium butyrate induces pancreatic progenitor formation, and directs the differentiation of mouse embryonic stem cells into hepatocytes when used in combination with the cytokine Activin A. Drug & Food Interactions. Website Help: Create Quote: . Best way to increase levels of butyrate in the gut The best method for someone to increase the amount of butyrate in their colon is to eat foods that are high in resistant starch and soluble fiber. Synonyms: Butyric acid sodium salt CAS Number: 156-54-7 Molecular Weight: 110.09 g/mol Chemical Formula: CH3CH2CH2COONa EINECS EC Number: 205-857-6. 110.09. Laboratory Reagent (LR) CAS. HS CODE. View pricing, availability and product specifications. Sodium butyrate special quality; CAS Number: 156-54-7; Synonyms: Sodium butyrate,Butyric acid sodium salt; find Sigma-Aldrich-817500 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich . Enterprises Mumbai, India 202, Shradanand Building 272/274, Samuel Street\\015\\012Masjid Bandar(W), Online . Body chemical composition Sodium butyrate at a dosage of 0.5 m M induced already a significant growth inhibition in all the three cell lines compared to mock-treated cells. Fuchikami M, Morinobu S, Segawa M, Matsumoto T, Yamawaki S. Antidepressant-like effect of sodium butyrate (HDAC inhibitor) and its molecular mechanism of action in the . . Sodium Butyrate. It is used for both induction and maintenance of ANESTHESIA. Grade. Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1. For Research Use Only. Sodium butyrate also augments transcription factor stimulated iPSC generation. Molecular Weight: 110.0871: Optical Activity: NONE Defined Stereocenters: 0 / 0: E/Z Centers: 0: . CAS Number, EINECS, Molecular Weight, Chemical Formula. Molecular Weight: 111.08. SDS Certificates. Sodium Butyrate: Sodium Carbonate: Sodium Citrate: Sodium Diacetate: Sodium Feredetate: Sodium Fluoride: Sodium Formate: Sodium Formaldehyde Bisulfite: Sodium Gluconate: . In one study , researchers found that sodium butyrate blocked the growth of colorectal cancer cells. Sodium butyrate induces pancreatic progenitor formation, and directs the differentiation of mouse embryonic stem cells into hepatocytes when used in combination with the cytokine Activin A. Formula Weight: 110.1 . Supplementation with nicotinamide and butyrate sodium can improve the meat quality of broilers. 98% * For isotopically labeled compounds, MW listed is for the fully enriched product. As one of the most professional sodium butyrate powder enterprises in China, we're featured by supplying high quality natural products. Product Name Sodium butyrate CAS 156-54-7 Tel 0086-551-65418679 Email sales@tnjchem.com info@tnjchem.com Molecular Weight* 111.08. Sodium butyrate | C4H7NaO2 | CID 5222465 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities . Molecular weight: 110.0869. Also Oklahoma, OK and Williston, ND USA . View pricing, availability and product specifications. Sodium butyrate in the form of enemas (combined in a mixture with A-300 silicon dioxide) may be a successful method of therapeutic management in patients with radiation proctitis. U87 cells were cultured with DMSO or 10 M 5azadC for 72 h. For the latter, 1 M Trichostatin A (TSA), 10 mM sodium butyrate (NaBu), 5 mM nicotinamide (NAM), or 0.5 M apicidin were added in the last 24 h. IFNLR1 expression was determined by RT-qPCR. In cells, this alters the expression of a select group of genes containing butyrate response elements and may also involve Sp1/Sp3 binding sites. 110.09 Solubility: soluble in water (500 mM), aliquot and store at -20 C Storage: 20 C. 200 . Inhibits histone deacetylase.Sodium butyrate is used in the treatment of human spinal muscular atrophy patients. Applications Decreases calcium release from intracellular stores. The invention provides a method for determining butyric acid and sodium butyrate by HPLC (High Performance Liquid Chromatography). Molecular Weight. Incubation with equimolar concentrations of tributyrin revealed stronger dose-dependent growth-inhibitory effects (data not shown). CAS Number: 156-54-7. . Name matches: p21 sodium butyrate. Chemical Formula: C 4 H 7 NaO 2. MFBOGIVSZKQAPD-UHFFFAOYSA-M Google Search Mol Weight: 110.09 g/mol: Molecular Formula: C4H7NaO2: Exact Mass: 110.034374 g/mol: Attenuated Total Reflectance Infrared (ATR-IR) Spectrum. Sodium butyratemore properly sodium butanoateis a salt of butyric (butanoic) acid. Sodium Butyrate. Test. Increased expression of histone H3 (acetyl K27) . Sodium Succinate SDS, Safety Data Sheet MSDS Sheet, Material Safety Data Sheet. This material is not classified dangerous good according to international transportation regulations (ADR/RID-IMDG-ICAO/IATA). Molecular basis of sodium butyrate-dependent proapoptotic activity in cancer cells 85 in DR5 (TRAIL-R2) mRNA level after NaBt treatment, but no CAS No - 156-54-7. 156-54-7. The effect of different levels (0 %, 0.3 % and 0.6 %) of a chemically protected sodium butyrate, Butirex C4 (BU), in diets formulated with different levels (45 %, 30 % and 15 %) of fishmeal (FM) on chemical body composition of pacific white shrimp (Litopenaeus vannamei). What is Sodium Butyrate? The number of electrons in each of Sodium's shells is [2, 8, 1] and its electron configuration is [Ne] 3s 1. MS Search. It revealed that the examined feed additive did not significantly modulate the immune response of the calves and a beneficial effect of using this . Various foods contain butyrate and we also produce it in our colons . The effect Sodium Butyrate (NaB) on body weight in HFD-fed mice. Pharmaco-omics. Sodium butyrate is a kind of histone deacetylases (HDACs) inhibitors studied clinically, which works on histones and transcription factors to modulate transcription [1]. However, the potential molecular mechanism is not clear yet. Induces apoptosis in several cell lines. Item List Price (USD) Sodium butyrate (NaB), a short chain . Purity: Greater than 98 % by acid base titration. It has long been known as an inhibitor of histone deacetylases (HDACs). Molecular Weight: 111.1. [CAS 156-54-7]. Sodium was . The chemical formula of butyrate is C4H7O2 and its name forms part of the various esters and salts of butyric acid including, Methyl butyrate, Butyl butyrate, Ethyl butyrate, Pentyl butyrate, and Sodium butyrate. The results of our study are in agreement with the literature, with rainbow trout (Oncorhynchus mykiss) (Gao et al., 2011; Ebrahimi et al., 2017) and tilapia (Oreochromis sp. Finoric LLC Beasley Houston Pleasanton Midland, Texas, USA. Molecular Formula: C4H7NaO2 Molecular Weight: 110.087. 110.09. MS/MS Search. Stability. Sodium butyrate also augments transcription factor stimulated iPSC generation. It is reported to induce apoptosis in a variety of cell lines and induce pancreatic progenitor formation. Previously, SH-SY5Y cells were studied as in vitro models of cerebral diseases. Butyrate, a low-molecular weight four-carbon chain volatile fatty acid (VFA) has been . Butyrate is a fatty acid that is fermented by anaerobes of dietary fiber, such as cellulose, in your colon, which can combine with sodium to form a salt called sodium butyrate. For more information call 1-800-282-3982 or email info@parchem.com! Data from [Data independently produced by Br J Haematol, 2014, 167 (5), 639-50] Synonym(s): 13 C Labeled sodium butyrate, Butyric acid-1-13 C sodium salt. Weight Average: 110.088 Monoisotopic: 110.03437375 Chemical Formula C 4 H 7 NaO 2 InChI Key Buy Sodium butyrate - an affordable, high quality Histone deacetylase (HDAC) inhibitor from Hello Bio, a trusted supplier for life science researchers worldwide . Hide. Synonyms: Butyric acid sodium salt CAS Number: 156-54-7, Molecular Weight: 110.09, Chemical Formula: CH3CH2CH2COONa, EINECS EC Number: 205-857-6, FEMA: ----, Sodium Butyrate USP Grade Specifications C4H7NaO2 -- 110.10 Butyric acid, sodium salt. Sodium butyrate is an organic compound with a molecular formula of C4H7O2Na and a molecular weight of 110.0869.. Solubility Soluble in water, dimethyl sulfoxide and ethanol. Molecular formula: C4H7NaO2. Target Sequences. 98% * For isotopically labeled compounds, MW listed is for the fully enriched product. Linear Formula: CH 3 . Solubility. It can be used in reprogramming of somatic cells into human induced pluripotent stem cells via induction of the miR302/367 cluster. Learn more about Sodium butyrate. Sodium Butyrate. . Interaction of HDACs and histone acetyltransferases determines histone acetylation, which affects the final transcription process. Notes Odor. Shelf Life - 36 months. Olfactory response to mushroom composting emissions as a . Sodium butyrate (NaB), whose chemical formula is CH 3 CH 2 CH 2 COONa (PubChem ID: 24858121, molecular weight: 110.09 g) was purchased from Sigma-Aldrich. CDH is an ISO certified Sodium Butyrate manufacturer in India, Sodium Butyrate (CAS-156-54-7) supplier & exporter in India. . All Photos (1) Sodium butyrate-13 C 4. Home; CAS; CAS 156; CAS 156-54-7 ; Sodium butyrate - Names and Identifiers. Molecular Weight (g/mol) 110.09: ChEBI: CHEBI:64103: Percent Purity: 98%: CAS: 156-54-7: Molecular Formula . The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. with special odor like corrupt cheese. Item List Price (USD) Further, it is used in the determination of the role of histone acetylation in chromatin structure and function. Butyrate is a fatty acid that is fermented by anaerobes of dietary fiber, such as cellulose, in your colon, which can combine with sodium to form a salt called sodium butyrate. Molecular Formulas C4-H7-Na-O3 C4-H7-O3.Na C4-H8-O3.Na Molecular Weight 126.0863 All Classifications Links to Resources Names & Synonyms Registry Numbers Formulas Structure Descriptors Toxicity Adjuvants, Anesthesia Anesthesia, Adjunct to Decreases Ca2+ release from intracellular stores. . 3.2. Sangherb, ISO 9001:2015 certified, is professional on Sodium butyrate with professional R&D team and strong R&D strength. . Inhibits histone deacetylase.Sodium butyrate is used in the treatment of human spinal muscular atrophy patients. Chemical Purity. Enquiry Now Back Active Product: Appearance: white crystalline solid with an unpleasant smell Brand name(s): Chemical Name: Molecular Weight: M.W. Formulation: White solid. Molecular Weight - 10.09 gm/mol. The method comprises the steps of injecting a precisely sucked standard substance solution and a test solution into a liquid chromatographic instrument, wherein a C18 chromatographic column is used, the mobile phase is formed by a 0.1% phosphoric acid solution with . Match Criteria: Product Name, Keyword. Inhibits histone deacetylase.Sodium butyrate is used in the treatment of human spinal muscular atrophy patients. We enable science by offering product choice, services, process excellence and our people make it happen. It has various effects on cultured mammalian cells including inhibition of proliferation, induction of differentiation and induction or repression of gene expression. See more Sodium products. EC Index Number: 205-857-6. Na. SpectraBase Compound ID . Molecular formula. . Find here Sodium Butyrate, Sodium Butanoate wholesaler & Wholesale Dealers in India. Insoluble in ether. stable in light or thermal environment, soluble in . Further, it is used in the determination of the role of histone acetylation in chromatin structure and function. Molecular Weight: 110.09. Formula. Description SDS Pricing; 292656: 99 atom % 13 C: Expand. CAS: 156-54-7. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Specifications Certificates Safety and Handling The most important observation is that butyrate supplementation at 5% wt/wt in high-fat diet prevented development of dietary obesity and insulin resistance. benefit to elevate weaning weight. (0 M) and different concentrations of sodium butyrate (ab120948). CAS: 156-54-7. . Sodium butyrate (NaB) is a short-chain fatty acid found in diet and produced in the gut that reportedly protects cancer, inflammation, obesity and so on. Molecular Weight: 110.09. . white or almost white powder. Sodium butyrate View entire compound with free spectra: 3 NMR, 4 FTIR, and 1 Raman. Sodium Butyrate is the sodium salt of butyric acid. Appearance. Molecular Formula C4H7NaO2 Molecular Weight 110.09 Price Inquiry Product Description Sodium butyrate is a HDAC inhibitor.